Por favor, use este identificador para citar o enlazar este ítem: http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2149
Título : Cellular immune response and Th1/Th2 cytokines in human neurocysticercosis: lack of immune suppression.
Creador: Medina Escutia, Edith
Nivel de acceso: Open access
Palabras clave : Citoquinas - biosíntesis
Tolerancia inmunológica
Neurocisticercosis - Inmunología
Cytokines - biosynthesis
Immune Tolerance
Neurocysticercosis - immunology
Descripción : Some reports have suggested that human neurocysticercosis (NCC) induces immunosuppression. To test this hypothesis, we performed a study on active cases of NCC who had not received cestocidal or immunosuppressive treatments. We examined blood counts and specific T cell markers (CD3, CD4, and CD8) by flow cytometry and found no differences between patients with NCC and healthy individuals. Both groups responded to concanavalin A (Con A), and patients with NCC responded more to a parasite crude antigen than uninfected individuals. Peripheral blood mononuclear cells were examined for interleukin (IL)-2, interferon-gamma, IL-10, and IL-4 mRNA. Regardless of infection status, more than 60% of individuals synthesized IL-2 mRNA and, less frequently, the other cytokines. These data suggest that immunosuppression does not occur in NCC patients.
Colaborador(es) u otros Autores: Morales López Zoila
Proaño Jefferson V
Vázquez José
Bermúdez Victor
Ortiz Navarrete Vianney
Madridmarina Vicente
Laclette Juan P
Correa Dolores
Fecha de publicación : 2001
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.1645/0022-3395(2001)087[0587:CIRATT]2.0.CO;2
Fuente: J Parasitol 87(3):587-590
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2149
Idioma: eng
Aparece en las colecciones: Artículos

Ficheros en este ítem:
No hay ficheros asociados a este ítem.


Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.