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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2149
Título : | Cellular immune response and Th1/Th2 cytokines in human neurocysticercosis: lack of immune suppression. |
Creador: | Medina Escutia, Edith |
Nivel de acceso: | Open access |
Palabras clave : | Citoquinas - biosíntesis Tolerancia inmunológica Neurocisticercosis - Inmunología Cytokines - biosynthesis Immune Tolerance Neurocysticercosis - immunology |
Descripción : | Some reports have suggested that human neurocysticercosis (NCC) induces immunosuppression. To test this hypothesis, we performed a study on active cases of NCC who had not received cestocidal or immunosuppressive treatments. We examined blood counts and specific T cell markers (CD3, CD4, and CD8) by flow cytometry and found no differences between patients with NCC and healthy individuals. Both groups responded to concanavalin A (Con A), and patients with NCC responded more to a parasite crude antigen than uninfected individuals. Peripheral blood mononuclear cells were examined for interleukin (IL)-2, interferon-gamma, IL-10, and IL-4 mRNA. Regardless of infection status, more than 60% of individuals synthesized IL-2 mRNA and, less frequently, the other cytokines. These data suggest that immunosuppression does not occur in NCC patients. |
Colaborador(es) u otros Autores: | Morales López Zoila Proaño Jefferson V Vázquez José Bermúdez Victor Ortiz Navarrete Vianney Madridmarina Vicente Laclette Juan P Correa Dolores |
Fecha de publicación : | 2001 |
Tipo de publicación: | Artículo |
Formato: | |
Identificador del Recurso : | 10.1645/0022-3395(2001)087[0587:CIRATT]2.0.CO;2 |
Fuente: | J Parasitol 87(3):587-590 |
URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2149 |
Idioma: | eng |
Aparece en las colecciones: | Artículos |
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