Por favor, use este identificador para citar o enlazar este ítem: http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2211
Título : Comparison of short-term treatment regimen of ciprofloxacin versus long-term treatment regimens of trimethoprim/sulfamethoxazole or norfloxacin for uncomplicated lower urinary tract infections: A randomized, multicentre, open-label, prospective study
Creador: Arredondo García, José Luis
Nivel de acceso: Open access
Palabras clave : Agentes Antibacterianos - uso terapéutico
Ciprofloxacina - administración y dosificación
Ciprofloxacina - uso terapéutico
Administración de Drogas
Norfloxacina - uso terapéutico
Sulfametoxazol - uso terapéutico
Trimetoprim - uso terapéutico
Infecciones del tracto urinario - quimioterapia
Anti-Bacterial Agents - therapeutic use
Ciprofloxacin - administration & dosage
Ciprofloxacin - therapeutic use
Drug Administration Schedule
Norfloxacin - therapeutic use
Sulfamethoxazole - therapeutic use
Trimethoprim - therapeutic use
Urinary Tract Infections - drug therapy
Fluoroquinolonas
Ensayos clínicos
Cistitis
América Latina
fluoroquinolones
clinical trials
cystitis
Latin America
Descripción : Objective: To compare the bacteriological and clinical efficacy of three treatments for uncomplicated cystitis in ambulatory pre-menopausal women: ciprofloxacin 250 mg orally twice daily for 3 days, trimethoprim/sulfamethoxazole 160/800 mg orally twice daily for 7 days, and norfloxacin 400 mg orally twice daily for 7 days. Materials and methods: A total of 455 women were randomly assigned to three treatment groups: 151 received ciprofloxacin, 150 received trimethoprim/sulfamethoxazole, and 154 received norfloxacin. Bacteriological cure and clinical resolution were evaluated 5-9 days and 4-6 weeks after completion of treatment. Results: There was no significant difference among the three treatment groups: overall efficacy ranged from 78.5% for the trimethoprim/sulfamethoxazole group, to 84.5% for the ciprofloxacin group. The highest overall incidence of drug-related adverse effects occurred in the trimethoprim/sulfamethoxazole patients. Conclusions: These data indicate that a 3 day treatment with ciprofloxacin is at least as clinically and bacteriologically effective as 7 day treatments with trimethoprim/sulfamethoxazole and norfloxacin for uncomplicated lower urinary tract infections. © The British Society for Antimicrobial Chemotherapy 2004; all rights reserved.
Colaborador(es) u otros Autores: Figueroa Damián R
Rosas A
Jáuregui A
Corral M
Costa A
Merlos RM
Ríos Fabra A
Amábile Cuevas CF
Hernández Oliva GM
Olguín J
Cardeñosa Guerra O
uUTI Latin American Study Group
Fecha de publicación : 2004
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.1093/jac/dkh414
Fuente: Journal of Antimicrobial Chemotherapy 54(4):840 - 843
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2211
Idioma: eng
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