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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2384| Título : | Eficacia y seguridad de la ciprofloxacina en el tratamiento de las infecciones de las vías urinarias (IVU) en adultos: Revisión sistemática con metaanálisis Efficacy and safety of ciprofloxacin in the treatment of urinary tract infections (UTI) in adults: A systematic review with meta-analysis |
| Creador: | Gutiérrez Castrellón, Pedro |
| Nivel de acceso: | Open access |
| Palabras clave : | Adulto Antibacterianos - administración & dosificación Antibacterianos - uso terapéutico Ciprofloxacino - efectos adversos Ciprofloxacino - uso terapéutico Humanos Ensayos Clínicos Controlados Aleatorios como Asunto Resultado del Tratamiento Infecciones Urinarias - quimioterapia Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Ciprofloxacin - adverse effects Ciprofloxacin - therapeutic use Humans Randomized Controlled Trials as Topic Treatment Outcome Urinary Tract Infections - drug therapy Ciprofloxacino Infección del tracto urinario Adulto Ciprofloxacin Urinary tract infection Adult |
| Descripción : | Objectives and Design: A systematic review with meta-analysis of randomized controlled trials (RCT) on the efficacy and safety of ciprofloxacin in the treatment of acute or complicated urinary tract infections in adults. Primary outcomes were bacteriological eradication, clinical cure, bacterial resistance, and adverse event rates. Results: Initially, 111 RCTs were identified. We excluded 81 studies due to low quality methodology. An analysis of the remaining RCTs identified therapeutic equivalence of ciprofloxacin against other antimicrobials in terms of bacterial eradication and clinical cure at the end of treatment and in subsequent stages. The percentage of bacterial resistance was similar in both groups, while the percentage of related adverse events was significantly lower in the groups treated with ciprofloxacin. Conclusions: We conclude that ciprofloxacin is a safe and effective therapeutic alternative for the treatment of acute or complicated urinary tract infections in adults. © 2015, Academia Nacional de Medicina. All rights reserved. |
| Colaborador(es) u otros Autores: | Ortíz-Hernández Anna Alejandra Llamosas-Gallardo Beatriz Acosta-Bastidas Mario A Jiménez-Gutiérrez Carlos Luisa Diaz-García Luisa Anzo-Osorio Anahi Estevez-Jiménez Juliana Jiménez-Escobar Irma Vidal-Vázquez Rosa Patricia |
| Fecha de publicación : | 2015 |
| Tipo de publicación: | Revisión |
| Formato: | |
| Fuente: | Gaceta Médica de México 151(2):225 - 244 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2384 |
| Idioma: | eng spa |
| Aparece en las colecciones: | Artículos |
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