Por favor, use este identificador para citar o enlazar este ítem: http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2397
Título : Esophageal anastomotic failure: an experimental study
Creador: Villegas Álvarez, Fernando
Nivel de acceso: Open access
Palabras clave : Anastomosis Quirúrgica - efectos adversos - Conejos
Peso Corporal - Conejos
Atresia Esofágica - cirugía - Conejos
Esófago - anatomía & histología - Conejos
Esófago - cirugía - Conejos
Distribución Aleatoria - Conejos
factores de riesgo - Conejos
Dehiscencia de la Herida Operatoria - Conejos
Tasa de Supervivencia - Conejos
Suturas - Conejos
Resistencia a la Tracción - Conejos
Insuficiencia del Tratamiento - Conejos
Anastomosis, Surgical -adverse effects - Rabbits
Body Weight - Rabbits
Esophageal Atresia - surgery - Rabbits
Esophagus - anatomy & histology - Rabbits
Esophagus - surgery - Rabbits
Random Allocation - Rabbits
Risk Factors - Rabbits
Surgical Wound Dehiscence - Rabbits
Survival Rate - Rabbits
Sutures - Rabbits
Tensile Strength - Rabbits
Treatment Failure - Rabbits
Atresia esofágica
Complicaciones de anastomosis quirúrgicas
Modo de animales quirúrgica
Esophageal atresia
Surgical anastomotic complications
Surgical animal mode
Descripción : Postsurgical complications in patients with esophageal atresia have remained unchanged during the last three decades. This study was aimed at investigating certain risk factors for small-sized esophageal anastomosis and to assess the probable relationship between esophageal length and body weight in rabbit. METHODS: Six groups of 10 adult rabbits were subjected to section or 1-cm segmental resection of thoracic esophagus followed by end-to-end anastomosis. Approximation strength of esophageal ends was measured. Three different suture materials were used, and three different surgeons carried out procedures. Observed morbidity was recorded, as well as leakage or stenosis frequency in suture line. Esophageal length and body weight of nonresected rabbits were measured. RESULTS: Fifteen leakages were observed in suture line; there were no differences in relative risk between groups with and without resection, or in ratio of this complication among surgeons; nonetheless, a greater number of leakages (p < 0.05) was observed at higher tension. There were no differences in magnitude of stenosis among surgeons, tension degree, or suture material used. Quadratic association was found between length of thoracic esophagus and body weight in nonresected rabbits. CONCLUSIONS: Rabbit esophagus is a suitable model to assess early surgical complications but not for late complications. Among three assessed factors, increased tension in patients with segmental deficit was the most significant factor in development of anastomotic leakage. Existence of nonlineal correlation between esophageal length and body weight in rabbit showed that resection of 1 cm of esophagus represented a different weight-dependent segmental deficit, which increased as weight decreased.
Colaborador(es) u otros Autores: Olvera Duran J
Rodríguez Aranda E
Carmona Mancilla A
Vigueras Villaseñor Rm
Méndez Ramírez I.
Fecha de publicación : 2003
Tipo de publicación: Artículo
Formato: PDF
Identificador del Recurso : 10.1016/S0188-4409(03)00028-6
Fuente: Archives of Medical Research 34(3):171-175
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2397
Idioma: eng
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