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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2524
Título : | Increased estrogen receptor alpha immunoreactivity in the forebrain of sexually satiated rats |
Creador: | Phillips Farfán, B.V. |
Nivel de acceso: | Open access |
Palabras clave : | Receptor alfa de Estrógeno - metabolismo - ratas Inmunohistoquímica - métodos - ratas Prosencéfalo - metabolismo - ratas Ratas Wistar Saciedad - fisiología - ratas Conducta Sexual Animal - fisiología - ratas Estrogen Receptor alpha - metabolism - rats Immunohistochemistry - methods - rats Prosencephalon - metabolism -rats Rats, Wistar Satiation - physiology - rats Sexual Behavior, Animal - physiology - rats Saciedad sexual Comportamiento sexual masculino Cerebro anterior Sistema límbico Receptor de estrógenos alfa Receptor de andrógenos Inmunocitoquímica Sexual satiety Masculine sexual behavior Forebrain Limbic system Estrogen receptor alpha Androgen receptor Immunocytochemistry |
Descripción : | Estrogen receptor alpha (ERα) participates in the neuroendocrine regulation of male sexual behavior, primarily in brain areas located in the limbic system. Males of many species present a long-term inhibition of sexual behavior after several ejaculations, known as sexual satiety. It has been shown that androgen receptor density is reduced 24 h after a single ejaculation or mating to satiety, in the medial preoptic area, nucleus accumbens and ventromedial hypothalamus. The aim of this study was to analyze if the density of ERα was also modified 24 h after a single ejaculation or mating to satiety. Sexual satiety was associated with an increased ERα density in the anteromedial bed nucleus of the stria terminalis (BSTMA), ventrolateral septum (LSV), posterodorsal medial amygdala (MePD), medial preoptic area (MPA) and nucleus accumbens core (NAc). A single ejaculation was related to an increase in ERα density in the BSTMA and MePD. ERα density in the arcuate (Arc) and ventromedial hypothalamic nuclei (VMN), and serum estradiol levels remained unchanged 24 h after one ejaculation or mating to satiety. These data suggest a relationship between sexual activity and an increase in the expression of ERα in specific brain areas, independently of estradiol levels in systemic circulation |
Colaborador(es) u otros Autores: | Lemus A. Fernández-Guasti |
Fecha de publicación : | 2007 |
Tipo de publicación: | Artículo |
Formato: | |
Identificador del Recurso : | 10.1016/j.yhbeh.2006.12.001 |
Fuente: | Hormones and Behavior 51(3):328-334 |
URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2524 |
Idioma: | eng |
Aparece en las colecciones: | Artículos |
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