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Título : Increased estrogen receptor alpha immunoreactivity in the forebrain of sexually satiated rats
Creador: Phillips Farfán, B.V.
Nivel de acceso: Open access
Palabras clave : Receptor alfa de Estrógeno - metabolismo - ratas
Inmunohistoquímica - métodos - ratas
Prosencéfalo - metabolismo - ratas
Ratas Wistar
Saciedad - fisiología - ratas
Conducta Sexual Animal - fisiología - ratas
Estrogen Receptor alpha - metabolism - rats
Immunohistochemistry - methods - rats
Prosencephalon - metabolism -rats
Rats, Wistar
Satiation - physiology - rats
Sexual Behavior, Animal - physiology - rats
Saciedad sexual
Comportamiento sexual masculino
Cerebro anterior
Sistema límbico
Receptor de estrógenos alfa
Receptor de andrógenos
Inmunocitoquímica
Sexual satiety
Masculine sexual behavior
Forebrain
Limbic system
Estrogen receptor alpha
Androgen receptor
Immunocytochemistry
Descripción : Estrogen receptor alpha (ERα) participates in the neuroendocrine regulation of male sexual behavior, primarily in brain areas located in the limbic system. Males of many species present a long-term inhibition of sexual behavior after several ejaculations, known as sexual satiety. It has been shown that androgen receptor density is reduced 24 h after a single ejaculation or mating to satiety, in the medial preoptic area, nucleus accumbens and ventromedial hypothalamus. The aim of this study was to analyze if the density of ERα was also modified 24 h after a single ejaculation or mating to satiety. Sexual satiety was associated with an increased ERα density in the anteromedial bed nucleus of the stria terminalis (BSTMA), ventrolateral septum (LSV), posterodorsal medial amygdala (MePD), medial preoptic area (MPA) and nucleus accumbens core (NAc). A single ejaculation was related to an increase in ERα density in the BSTMA and MePD. ERα density in the arcuate (Arc) and ventromedial hypothalamic nuclei (VMN), and serum estradiol levels remained unchanged 24 h after one ejaculation or mating to satiety. These data suggest a relationship between sexual activity and an increase in the expression of ERα in specific brain areas, independently of estradiol levels in systemic circulation
Colaborador(es) u otros Autores: Lemus
A. Fernández-Guasti
Fecha de publicación : 2007
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.1016/j.yhbeh.2006.12.001
Fuente: Hormones and Behavior 51(3):328-334
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2524
Idioma: eng
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