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Título : Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)
Creador: Calderón Guzmán, David
Nivel de acceso: Open access
Palabras clave : Resistencia a la Insulina - fisiología
Enfermedades Neurodegenerativas - metabolismo
Insulina - metabolismo
Insulina - uso terapéutico
Obesidad - etiología
Obesidad - metabolismo
Obesidad - terapia
Factores de Riesgo
Obesidad - prevención & control
Encéfalo - efectos de drogas
Encéfalo - metabolismo
Estrés Oxidativo
Sistema Nervioso Central - metabolismo
Enfermedad de Alzheimer - metabolismo
Enfermedad de Parkinson - metabolismo
Insulin Resistance - physiology
Neurodegenerative Diseases - metabolism
Insulin -metabolism
Insulin -Therapeutic use
Obesity - etiology
Obesity - metabolism
Obesity - therapy
Risk Factors
Obesity - prevention & control
Brain - efectos de drogas
Brain - metabolism
Oxidative Stress
Central Nervous System - metabolism
Alzheimer Disease - metabolism
Parkinson Disease - metabolism
medicamentos antidiabéticos; sistema nervioso central; insulina; enfermedades neurodegenerativas; obesidad
antidiabetic drugs; central nervous system; insulin; neurodegenerative disorders; obesity
Descripción : Insulin is a peptide that can be harmful with regards to neuroplasticity, neuroprotection and neuromodulation. Furthermore, the role of insulin highlights its relevance in the progress of diverse clinical disorders as well as in the mechanisms associated with certain pathogenesis and their evolution towards diabetes, obesity and neurodegenerative diseases. The precise molecular mechanisms by which these diseases are induced remain to be elucidated. The benefits in knowing/discovering these mechanisms in animal models and humans cannot be undermined. An in depth understanding of the principal risk factors leading to obesity and their management is vital in the implementation of early-life strategies of intervention and prevention, with a view to avoid adverse late-life outcomes. Therefore, the aim of the present study was to review their possible association with antidiabetic drugs
Colaborador(es) u otros Autores: Juárez-Olguín Mateo Hugo
Hernández-García Ernestina
Ortiz-Herrera N
Osnaya Brizuela Norma
Fecha de publicación : 2016
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.3892/br.2016.616
Fuente: Biomed Rep. 4(4):395-399
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2605
Idioma: spa
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