Por favor, use este identificador para citar o enlazar este ítem: http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2828
Título : Streptococcus pneumoniae as cause of infection in infants less than 60 days of age: Serotypes and antimicrobial susceptibility
Creador: Soto Noguerón Araceli
Nivel de acceso: Open access
Palabras clave : Femenino
Humanos
lactante
Recién nacido
masculino
Pruebas de Sensibilidad Microbiana
Infecciones Neumocócicas - microbiología
Estudios Retrospectivos
Serotipificación
Streptococcus pneumoniae - clasificación
Streptococcus pneumoniae - efectos de drogas
Female
Humans
Infant
Infant, Newborn
Male
Microbial Sensitivity Tests
Pneumococcal Infections/microbiology* Retrospective Studies Serotyping Streptococcus pneumoniae/classification* Streptococcus pneumoniae/drug effects
Antimicrobial susceptibility; Invasive pneumococcal diseases; Newborns; Pneumococcal vaccines; Serotypes; Streptococcus pneumoniae
Antimicrobial susceptibility; Invasive pneumococcal diseases; Newborns; Pneumococcal vaccines; Serotypes; Streptococcus pneumoniae
Descripción : Objective: The aim of this study was to determine the distribution of serotypes and the antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates causing invasive and non-invasive disease in children aged ≤60 days in hospitals in Mexico. Methods: A 15-year retrospective study was conducted for the period 2000 to 2014. Pneumococcal clinical isolates were serotyped by Quellung reaction, and antimicrobial susceptibility testing was performed with the broth microdilution method. Results: A total of 126 pneumococcal isolates were collected. Pneumonia was the most frequent diagnosis (40.5%), followed by meningitis (29.4%), septicemia (16.7%), and other clinical entities, including otitis media and conjunctivitis (13.5%). The most frequent serotypes before the introduction of heptavalent pneumococcal conjugate vaccine (PCV7) were 19F, 23F, 7F, and 35B. Serotypes 3, 6A, 10A, 12F, and 15A/B increased after the introduction of PCV7. Serotype 19A was isolated most frequently in the pneumonia and meningitis cases only after the introduction of PCV7, and it displayed a high resistance to penicillin. Conclusions: Although the number of infections in infants aged ≤60 days was low, such infections were not unusual events. New vaccination strategies should be evaluated to limit the risks in this age group. © 2015 The Authors.
Colaborador(es) u otros Autores: Carnalla-Barajas María Noemí
Solórzano-Santos Fortino
Arrendondo-García José Luis
Arzate-Barbosa Patricia
Tinoco-Favila Juan Carlos
Anzurez-Gutiérrez Azarell
Echániz-Aviles Gabriela
Fecha de publicación : 2016
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.1016/j.ijid.2015.12.001
Fuente: International Journal of Infectious Diseases 42():69 - 73
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2828
Idioma: eng
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