1. Instituto Nacional de Pediatría
2. INP
3. Artículos Investigadores

Título :	Identification of CD4 + T cell epitopes of Taenia solium paramyosin.
Creador:	HECTOR SAMUEL LOPEZ MORENO MARIA DOLORES CORREA BELTRAN JUAN PEDRO LACLETTE SN ROMAN VIANNEY FRANCISCO ORTIZ NAVARRETE
Nivel de acceso:	Acceso Abierto
Palabras clave :	MEDICINA Y CIENCIAS DE LA SALUD Linfocitos T CD4-Positivos - Inmunología Cisticercosis - Inmunología Epítopos de Linfocito T - Química Taenia solium - Inmunología Tropomiosina - Inmunología CD4-Positive T - Lymphocytes - Immunology Cysticercosis - Immunology Epitopes, T - Lymphocyte - Chemistry Taenia solium - Immunology Tropomyosin - Immunology Taenia solium paramiosina Epítopo de célula T CD4 + Cisticercosis I-Ad Taenia solium paramyosin CD4+ T cell epitope Cysticercosis
Descripción :	T cell mediated response is involved in a protective immune response against experimental cysticercosis conferred by immunization with Taenia solium paramyosin (TPmy) to BALB/c mice. In this study, we analysed the TPmy amino acid sequence for predicted CD4+ T cells epitopes. Five different regions of this protein showed that the residues anchor to bind the I-A d molecule; synthetic peptides containing these epitopes were evaluated for their ability to induce lymphoproliferative responses of spleen cells from TPmy immunized mice. Among them, Tp176 (amino acids 176-192 sequence DDLQRQMADANSAKSRL) was the immunodominant T cell epitope of TPmy. Delineation of this epitope should facilitate analysis of the role of CD4+ T cell response in experimental cysticercosis.
Editorial :	Wiley
Fecha de publicación :	2003
Tipo de publicación:	Artículo
Formato:	Adobe PDF
Identificador del Recurso :	10.1111/j.1365-3024.2003.00658.x
Fuente:	Parasite Immunology 25(10):513 - 516
URI :	http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/3111
Aparece en las colecciones:	Artículos Investigadores

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