1. Instituto Nacional de Pediatría
2. INP
3. Artículos Investigadores

Título :	Cytotoxic and antimutagenic effects of sodium selenite.
Creador:	FIKRAT ABDULLAEV JAFAROVA LETICIA RIVERON NEGRETE ELEAZAR ISRAEL PEREZ LOPEZ RAFAEL CAMACHO CARRANZA JESUS JAVIER ESPINOSA AGUIRRE
Nivel de acceso:	Acceso Abierto
Palabras clave :	MEDICINA Y CIENCIAS DE LA SALUD Selenito de sodio - Toxicidad Antimutagénicos Sodium selenite - Toxicity Antimutagenic agents Selenito de sodio Citotoxicidad Mutagenicidad Fermentaciones Quimioprevención Sodium selenite Cytotoxicity Mutagenicity Antimutagenicity Chemoprevention
Descripción :	In the last decade, there is an increasing interest in selenium compounds because of their environmental, biological, and toxicological importance, and in particular, because of their anticancer activities. We have examined the effect of sodium selenite on colony formation of different human cultured malignant cells. In addition, the antimutagenic activities of this chemical was examined against the indirect-acting mutagen benzo[a]pyrene (BP) by using the Ames/Salmonella test assay TA98 strain. Results of these experiments demonstrated that sodium selenite caused a dose-dependent inhibitory effect on colony formation of tested malignant cells. It was also shown that sodium selenite exhibited dose-dependent antimutagenic effect on BP. These results suggest the potential use of selenium compounds as an anticancer and antimutagenic agent.
Editorial :	Centro de Ciencias de la Atmósfera, UNAM
Fecha de publicación :	2005
Tipo de publicación:	Artículo
Formato:	Adobe PDF
Fuente:	Rev Int Contam Ambie 21(Suppl 1):85-89
URI :	http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/3115
Aparece en las colecciones:	Artículos Investigadores

Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.